CRCGN016_MCF10A.TP53.M_24H:F22 Gene Set
Genes
20 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:F22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCB6
|
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
|
3.68587
|
|
IDE
|
insulin-degrading enzyme
|
3.47693
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
2.95543
|
|
MAP7
|
microtubule-associated protein 7
|
2.83027
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
2.65355
|
|
TMEM50A
|
transmembrane protein 50A
|
2.46762
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
2.38328
|
|
PRKCH
|
protein kinase C, eta
|
2.22704
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB1
|
cyclin B1
|
-3.75427
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.69287
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-3.19892
|
|
MT2A
|
metallothionein 2A
|
-3.11828
|
|
PSMD2
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
|
-2.94757
|
|
MT1X
|
metallothionein 1X
|
-2.80354
|
|
HMG20B
|
high mobility group 20B
|
-2.7351
|
|
GOLT1B
|
golgi transport 1B
|
-2.66029
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.40724
|
|
POLR2H
|
polymerase (RNA) II (DNA directed) polypeptide H
|
-2.36177
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.32216
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.08024
|
