CRCGN016_MCF10A.TP53.M_24H:F23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-methylaniline 33.54 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:F23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.5561
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 4.53908
CCP110 centriolar coiled coil protein 110kDa 4.51791
SNAP25 synaptosomal-associated protein, 25kDa 4.47244
AGR2 anterior gradient 2 4.38636
STX1A syntaxin 1A (brain) 3.36615
RAB21 RAB21, member RAS oncogene family 3.10462
ZNF586 zinc finger protein 586 3.04545
MELK maternal embryonic leucine zipper kinase 2.55841
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 2.27589
CHGB chromogranin B 2.12639

decreased expression

Symbol Name Standardized Value
TARBP1 TAR (HIV-1) RNA binding protein 1 -5.33089
ENOPH1 enolase-phosphatase 1 -5.01626
C2CD5 C2 calcium-dependent domain containing 5 -4.75441
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -4.3391
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.2206
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) -2.44847
TCTA T-cell leukemia translocation altered -2.40876