CRCGN016_MCF10A.TP53.M_24H:G04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description alpha-methyldopa sesquihydrate 100.97 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:G04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCL2 chemokine (C-X-C motif) ligand 2 5.42487
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.36471
TSEN2 TSEN2 tRNA splicing endonuclease subunit 3.66054

decreased expression

Symbol Name Standardized Value
TEX10 testis expressed 10 -4.96799
DIPK1A divergent protein kinase domain 1A -3.68701
KRT14 keratin 14, type I -2.9863
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.41058
HSPA1A heat shock 70kDa protein 1A -2.27946
RPIA ribose 5-phosphate isomerase A -2.21504
NOSIP nitric oxide synthase interacting protein -2.18091
COG2 component of oligomeric golgi complex 2 -2.134
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.06489
LYPLA1 lysophospholipase I -2.04055