CRCGN016_MCF10A.TP53.M_24H:G05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description alpha-methyldopa sesquihydrate 33.66 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:G05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FKBP14 FK506 binding protein 14, 22 kDa 5.18635
ABHD4 abhydrolase domain containing 4 4.6184
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.36488
COMP cartilage oligomeric matrix protein 3.06872
DENND2D DENN/MADD domain containing 2D 2.99881
NRBF2 nuclear receptor binding factor 2 2.85277
ACAA1 acetyl-CoA acyltransferase 1 2.39109
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.23525

decreased expression

Symbol Name Standardized Value
MT1X metallothionein 1X -3.7138
NUSAP1 nucleolar and spindle associated protein 1 -3.34183
SMC1A structural maintenance of chromosomes 1A -2.66362
KRT14 keratin 14, type I -2.24044
PIH1D1 PIH1 domain containing 1 -2.06988
PRCP prolylcarboxypeptidase (angiotensinase C) -2.0457
FAM114A2 family with sequence similarity 114, member A2 -2.01035