| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4,4'-methylene-bis(2-chloro?aniline) 32.65 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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86 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:G08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 4.8355 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 4.59846 |
| ATP11B | ATPase, class VI, type 11B | 4.11409 |
| STAP2 | signal transducing adaptor family member 2 | 3.50168 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.44292 |
| KIF5C | kinesin family member 5C | 3.18455 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.02734 |
| DUSP2 | dual specificity phosphatase 2 | 2.96908 |
| FCHO1 | FCH domain only 1 | 2.93273 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | 2.83436 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 2.75488 |
| RSF1 | remodeling and spacing factor 1 | 2.70565 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 2.69963 |
| WRN | Werner syndrome, RecQ helicase-like | 2.69205 |
| TBXA2R | thromboxane A2 receptor | 2.64501 |
| THAP12 | THAP domain containing 12 | 2.63096 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 2.50113 |
| ZNF12 | zinc finger protein 12 | 2.4791 |
| PID1 | phosphotyrosine interaction domain containing 1 | 2.39185 |
| CCN6 | cellular communication network factor 6 | 2.36885 |
| NCLN | nicalin | 2.34982 |
| PKN1 | protein kinase N1 | 2.34478 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.34128 |
| CLCA2 | chloride channel accessory 2 | 2.33152 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 2.29887 |
| THAP4 | THAP domain containing 4 | 2.28609 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 2.28273 |
| RASSF9 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 | 2.24743 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.22971 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 2.20026 |
| GTPBP6 | GTP binding protein 6 (putative) | 2.15453 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | 2.1518 |
| ZBTB48 | zinc finger and BTB domain containing 48 | 2.14397 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | 2.1399 |
| PRTN3 | proteinase 3 | 2.11256 |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 | 2.09466 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 2.08137 |
| KAT6B | K(lysine) acetyltransferase 6B | 2.07742 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 2.07259 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.03957 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 | 2.03598 |
| E2F8 | E2F transcription factor 8 | 2.01499 |
| RASL11B | RAS-like, family 11, member B | 2.00597 |
| BCOR | BCL6 corepressor | 2.00547 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ENOPH1 | enolase-phosphatase 1 | -5.30709 |
| PCNA | proliferating cell nuclear antigen | -4.91175 |
| SLC35F2 | solute carrier family 35, member F2 | -4.70032 |
| RALGDS | ral guanine nucleotide dissociation stimulator | -4.30742 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.73043 |
| NGRN | neugrin, neurite outgrowth associated | -3.40383 |
| ADRB2 | adrenoceptor beta 2, surface | -3.22572 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -2.98556 |
| PFN1 | profilin 1 | -2.84626 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.70464 |
| SASH3 | SAM and SH3 domain containing 3 | -2.61636 |
| RBM34 | RNA binding motif protein 34 | -2.60372 |
| FASN | fatty acid synthase | -2.56201 |
| DUSP14 | dual specificity phosphatase 14 | -2.55013 |
| ATG3 | autophagy related 3 | -2.49872 |
| RAB8A | RAB8A, member RAS oncogene family | -2.45091 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -2.43841 |
| STMN1 | stathmin 1 | -2.42663 |
| RGS2 | regulator of G-protein signaling 2 | -2.40876 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -2.39843 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -2.37629 |
| MSN | moesin | -2.36476 |
| TCEA2 | transcription elongation factor A (SII), 2 | -2.3164 |
| GGPS1 | geranylgeranyl diphosphate synthase 1 | -2.31426 |
| PRKCZ | protein kinase C, zeta | -2.29721 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -2.23487 |
| NOSIP | nitric oxide synthase interacting protein | -2.22506 |
| SNX5 | sorting nexin 5 | -2.16888 |
| MCM6 | minichromosome maintenance complex component 6 | -2.15756 |
| RPS5 | ribosomal protein S5 | -2.13445 |
| CHMP1A | charged multivesicular body protein 1A | -2.11692 |
| SAP30BP | SAP30 binding protein | -2.11522 |
| SNX10 | sorting nexin 10 | -2.10426 |
| SNRPB2 | small nuclear ribonucleoprotein polypeptide B | -2.09729 |
| LAPTM5 | lysosomal protein transmembrane 5 | -2.08669 |
| FNDC4 | fibronectin type III domain containing 4 | -2.08637 |
| PSMG2 | proteasome (prosome, macropain) assembly chaperone 2 | -2.08285 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -2.07759 |
| CAB39 | calcium binding protein 39 | -2.07644 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.07568 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -2.07224 |
| DSTN | destrin (actin depolymerizing factor) | -2.00213 |
