CRCGN016_MCF10A.TP53.M_24H:G11 Gene Set
Genes
52 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:G11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.1562
|
|
ELAC2
|
elaC ribonuclease Z 2
|
3.88012
|
|
NUP93
|
nucleoporin 93kDa
|
3.66747
|
|
LYRM1
|
LYR motif containing 1
|
3.07869
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
2.72926
|
|
PLK1
|
polo-like kinase 1
|
2.66993
|
|
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6
|
2.51872
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
2.46355
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.44588
|
|
LY6E
|
lymphocyte antigen 6 complex, locus E
|
2.39776
|
|
ERAL1
|
Era-like 12S mitochondrial rRNA chaperone 1
|
2.36926
|
|
TERF2IP
|
telomeric repeat binding factor 2, interacting protein
|
2.33179
|
|
RUVBL1
|
RuvB-like AAA ATPase 1
|
2.32409
|
|
EVA1B
|
eva-1 homolog B (C. elegans)
|
2.27072
|
|
MTHFD2
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
|
2.19858
|
|
PES1
|
pescadillo ribosomal biogenesis factor 1
|
2.19679
|
|
ATP13A1
|
ATPase type 13A1
|
2.18731
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
2.17587
|
|
ATP6V0B
|
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
|
2.17256
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
2.1613
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.11815
|
|
NUP85
|
nucleoporin 85kDa
|
2.11404
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.11325
|
|
EBNA1BP2
|
EBNA1 binding protein 2
|
2.0769
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
2.06492
|
|
COLGALT1
|
collagen beta(1-O)galactosyltransferase 1
|
2.05098
|
|
CTSW
|
cathepsin W
|
2.04906
|
|
PPIE
|
peptidylprolyl isomerase E (cyclophilin E)
|
2.04726
|
|
FAH
|
fumarylacetoacetate hydrolase (fumarylacetoacetase)
|
2.01829
|
|
IGF2BP2
|
insulin-like growth factor 2 mRNA binding protein 2
|
2.01197
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ACOT9
|
acyl-CoA thioesterase 9
|
-3.31354
|
|
RSU1
|
Ras suppressor protein 1
|
-3.21139
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
-2.96004
|
|
FRS2
|
fibroblast growth factor receptor substrate 2
|
-2.61786
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.58133
|
|
MPC2
|
mitochondrial pyruvate carrier 2
|
-2.54487
|
|
BUB1B
|
BUB1 mitotic checkpoint serine/threonine kinase B
|
-2.50201
|
|
CASC3
|
cancer susceptibility candidate 3
|
-2.39924
|
|
GTF2A2
|
general transcription factor IIA, 2, 12kDa
|
-2.26909
|
|
SLC35A1
|
solute carrier family 35 (CMP-sialic acid transporter), member A1
|
-2.26561
|
|
KCTD20
|
potassium channel tetramerization domain containing 20
|
-2.26216
|
|
SCYL2
|
SCY1-like 2 (S. cerevisiae)
|
-2.17631
|
|
MBTPS1
|
membrane-bound transcription factor peptidase, site 1
|
-2.17164
|
|
MAPRE1
|
microtubule-associated protein, RP/EB family, member 1
|
-2.14835
|
|
MTMR12
|
myotubularin related protein 12
|
-2.14405
|
|
OR7A5
|
olfactory receptor, family 7, subfamily A, member 5
|
-2.12864
|
|
ABHD17B
|
abhydrolase domain containing 17B
|
-2.11836
|
|
LDHD
|
lactate dehydrogenase D
|
-2.10509
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.0963
|
|
SPRING1
|
SREBF pathway regulator in golgi 1
|
-2.05135
|
|
PDHA1
|
pyruvate dehydrogenase (lipoamide) alpha 1
|
-2.01751
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-2.00291
|
