CRCGN016_MCF10A.TP53.M_24H:G12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description erythrosine 11.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

73 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:G12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase 5.05073
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.82436
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 4.73975
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 3.61396
BMP4 bone morphogenetic protein 4 3.42645
VGLL4 vestigial-like family member 4 3.32817
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 3.20356
PPOX protoporphyrinogen oxidase 3.1742
INTS3 integrator complex subunit 3 3.12206
TLCD3A TLC domain containing 3A 2.71931
KDM5D lysine (K)-specific demethylase 5D 2.69259
JMJD1C jumonji domain containing 1C 2.64664
COMP cartilage oligomeric matrix protein 2.51215
TRAPPC4 trafficking protein particle complex 4 2.50071
CH25H cholesterol 25-hydroxylase 2.4624
HLA-DRA major histocompatibility complex, class II, DR alpha 2.40004
LYN LYN proto-oncogene, Src family tyrosine kinase 2.39498
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.38612
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 2.37577
NRBF2 nuclear receptor binding factor 2 2.37345
TSPAN3 tetraspanin 3 2.35054
PCYOX1L prenylcysteine oxidase 1 like 2.32926
TMEM109 transmembrane protein 109 2.32621
LGALS1 lectin, galactoside-binding, soluble, 1 2.30066
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.27152
BST2 bone marrow stromal cell antigen 2 2.27123
SPAG4 sperm associated antigen 4 2.22854
NUP93 nucleoporin 93kDa 2.20762
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 2.15839
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 2.15335
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.07175
CCDC6 coiled-coil domain containing 6 2.07142
JPT1 Jupiter microtubule associated homolog 1 2.06941
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 2.03386

decreased expression

Symbol Name Standardized Value
ISOC1 isochorismatase domain containing 1 -4.31267
CCDC86 coiled-coil domain containing 86 -4.27046
CHMP4B charged multivesicular body protein 4B -3.55699
KDM5C lysine (K)-specific demethylase 5C -3.01573
PPIC peptidylprolyl isomerase C (cyclophilin C) -3.00568
S100A1 S100 calcium binding protein A1 -2.6497
GFRA1 GDNF family receptor alpha 1 -2.58486
SIX6 SIX homeobox 6 -2.57502
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein -2.53184
FOLR3 folate receptor 3 (gamma) -2.41714
COTL1 coactosin-like F-actin binding protein 1 -2.40546
TESPA1 thymocyte expressed, positive selection associated 1 -2.39812
FKRP fukutin related protein -2.36514
CAMK4 calcium/calmodulin-dependent protein kinase IV -2.35887
ANO3 anoctamin 3 -2.3404
SOX5 SRY (sex determining region Y)-box 5 -2.29978
HPCA hippocalcin -2.25738
RUSF1 RUS family member 1 -2.2006
SMC1A structural maintenance of chromosomes 1A -2.19727
EPHB6 EPH receptor B6 -2.1972
ALOX15B arachidonate 15-lipoxygenase, type B -2.19677
TEX10 testis expressed 10 -2.19606
PDE8B phosphodiesterase 8B -2.15819
BASP1 brain abundant, membrane attached signal protein 1 -2.1526
BAD BCL2-associated agonist of cell death -2.14227
LOC107985101 uncharacterized LOC107985101 -2.14132
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -2.13666
SCN8A sodium channel, voltage gated, type VIII alpha subunit -2.11501
ATP11B ATPase, class VI, type 11B -2.11199
TRAPPC6A trafficking protein particle complex 6A -2.09329
SIM1 single-minded family bHLH transcription factor 1 -2.08905
LIN7A lin-7 homolog A (C. elegans) -2.07365
PUDP pseudouridine 5'-phosphatase -2.05922
TRMT61A tRNA methyltransferase 61A -2.03022
PAX9 paired box 9 -2.02673
NME8 NME/NM23 family member 8 -2.02308
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 -2.01323
TSHB thyroid stimulating hormone, beta -2.0078
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta -2.00482