| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sirolimus 3.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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84 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:G17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCP110 | centriolar coiled coil protein 110kDa | 4.30503 |
| UBQLN2 | ubiquilin 2 | 4.30447 |
| MAMLD1 | mastermind-like domain containing 1 | 4.28066 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.18639 |
| CNPY3 | canopy FGF signaling regulator 3 | 3.88993 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.62589 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 3.50745 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 3.3249 |
| RELN | reelin | 3.18844 |
| HMGA2 | high mobility group AT-hook 2 | 3.10825 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.8685 |
| EPHB2 | EPH receptor B2 | 2.86536 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.75836 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 2.75698 |
| RLIM | ring finger protein, LIM domain interacting | 2.74966 |
| FHL2 | four and a half LIM domains 2 | 2.74521 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 2.70351 |
| SCCPDH | saccharopine dehydrogenase (putative) | 2.68418 |
| TSPAN6 | tetraspanin 6 | 2.65485 |
| SRPX | sushi-repeat containing protein, X-linked | 2.58022 |
| TSPAN4 | tetraspanin 4 | 2.48917 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 2.48026 |
| CDCA4 | cell division cycle associated 4 | 2.31924 |
| DUSP6 | dual specificity phosphatase 6 | 2.30524 |
| GOLGA3 | golgin A3 | 2.2831 |
| RALGDS | ral guanine nucleotide dissociation stimulator | 2.25887 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | 2.25813 |
| FANCC | Fanconi anemia, complementation group C | 2.25458 |
| ZIC1 | Zic family member 1 | 2.22655 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 2.20088 |
| TMEM50A | transmembrane protein 50A | 2.19518 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 2.18667 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 | 2.17134 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.10521 |
| HMBOX1 | homeobox containing 1 | 2.08757 |
| CHGB | chromogranin B | 2.0848 |
| DUSP4 | dual specificity phosphatase 4 | 2.08314 |
| TP53 | tumor protein p53 | 2.07269 |
| RNF220 | ring finger protein 220 | 2.06046 |
| NOP53 | NOP53 ribosome biogenesis factor | 2.06 |
| EP400 | E1A binding protein p400 | 2.05901 |
| AOX1 | aldehyde oxidase 1 | 2.05116 |
| CEP170 | centrosomal protein 170kDa | 2.02796 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 2.02737 |
| TGM2 | transglutaminase 2 | 2.00035 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TUBA4A | tubulin, alpha 4a | -5.26022 |
| MSMO1 | methylsterol monooxygenase 1 | -4.48611 |
| HSPB1 | heat shock 27kDa protein 1 | -3.81102 |
| SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 | -3.66168 |
| PRR15L | proline rich 15-like | -3.66001 |
| JMJD6 | jumonji domain containing 6 | -3.62404 |
| DDIT4 | DNA-damage-inducible transcript 4 | -3.51031 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.35418 |
| CORO1A | coronin, actin binding protein, 1A | -3.32514 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -3.11536 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.04219 |
| REEP5 | receptor accessory protein 5 | -3.00554 |
| AURKB | aurora kinase B | -3.00194 |
| S100A8 | S100 calcium binding protein A8 | -2.81769 |
| S100A4 | S100 calcium binding protein A4 | -2.78671 |
| STK17B | serine/threonine kinase 17b | -2.7788 |
| MXRA7 | matrix-remodelling associated 7 | -2.75383 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -2.67353 |
| INSIG1 | insulin induced gene 1 | -2.57054 |
| ALDOC | aldolase C, fructose-bisphosphate | -2.54902 |
| TSC22D3 | TSC22 domain family, member 3 | -2.51757 |
| STAP2 | signal transducing adaptor family member 2 | -2.4395 |
| SAP30BP | SAP30 binding protein | -2.38806 |
| ZNF274 | zinc finger protein 274 | -2.38476 |
| INPP1 | inositol polyphosphate-1-phosphatase | -2.26407 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 | -2.23069 |
| TK1 | thymidine kinase 1, soluble | -2.20296 |
| CBR1 | carbonyl reductase 1 | -2.18071 |
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 | -2.17728 |
| PEX13 | peroxisomal biogenesis factor 13 | -2.17247 |
| INTS12 | integrator complex subunit 12 | -2.17169 |
| BAD | BCL2-associated agonist of cell death | -2.16714 |
| MAIP1 | matrix AAA peptidase interacting protein 1 | -2.14039 |
| ANKRD10 | ankyrin repeat domain 10 | -2.0983 |
| LBR | lamin B receptor | -2.09707 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | -2.0871 |
| ATP5PD | ATP synthase peripheral stalk subunit d | -2.08519 |
| H2BC12 | H2B clustered histone 12 | -2.03891 |
| POMP | proteasome maturation protein | -2.01858 |
