| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sirolimus 1.11 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:G18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | 3.85647 |
| TMEM50A | transmembrane protein 50A | 3.569 |
| PDLIM1 | PDZ and LIM domain 1 | 3.17669 |
| E2F2 | E2F transcription factor 2 | 3.13234 |
| FHL2 | four and a half LIM domains 2 | 3.02529 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 2.98201 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 2.95931 |
| FGFR4 | fibroblast growth factor receptor 4 | 2.81405 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | 2.73312 |
| KIF5C | kinesin family member 5C | 2.64795 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 2.63244 |
| TSPAN4 | tetraspanin 4 | 2.62283 |
| SCCPDH | saccharopine dehydrogenase (putative) | 2.61973 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 2.61007 |
| TLCD3A | TLC domain containing 3A | 2.51436 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 2.26658 |
| NLRP4 | NLR family, pyrin domain containing 4 | 2.25423 |
| IDE | insulin-degrading enzyme | 2.25184 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 2.23518 |
| PLSCR1 | phospholipid scramblase 1 | 2.14613 |
| CDCA4 | cell division cycle associated 4 | 2.09866 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.06175 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.05696 |
| CIRBP | cold inducible RNA binding protein | 2.0279 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PRR15L | proline rich 15-like | -4.04268 |
| TUBA4A | tubulin, alpha 4a | -3.9157 |
| HSPB1 | heat shock 27kDa protein 1 | -3.72548 |
| HSPA8 | heat shock 70kDa protein 8 | -3.271 |
| TRIB3 | tribbles pseudokinase 3 | -3.20294 |
| DDIT4 | DNA-damage-inducible transcript 4 | -3.05296 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -3.01343 |
| CORO1A | coronin, actin binding protein, 1A | -2.95727 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -2.86731 |
| INSIG1 | insulin induced gene 1 | -2.85269 |
| CD58 | CD58 molecule | -2.81907 |
| ALDOC | aldolase C, fructose-bisphosphate | -2.73337 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -2.68957 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -2.55572 |
| CLDN4 | claudin 4 | -2.44169 |
| SMNDC1 | survival motor neuron domain containing 1 | -2.41932 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | -2.4106 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | -2.38893 |
| ARFIP2 | ADP-ribosylation factor interacting protein 2 | -2.34695 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -2.31305 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -2.29012 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | -2.27293 |
| ABHD4 | abhydrolase domain containing 4 | -2.24343 |
| SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 | -2.23825 |
| STAP2 | signal transducing adaptor family member 2 | -2.2236 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | -2.21947 |
| S100A4 | S100 calcium binding protein A4 | -2.21611 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -2.16595 |
| TSC22D3 | TSC22 domain family, member 3 | -2.16341 |
| PUS3 | pseudouridylate synthase 3 | -2.06788 |
| SESN1 | sestrin 1 | -2.05567 |
