CRCGN016_MCF10A.TP53.M_24H:G19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-amino-5-nitrothiazole 96.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

14 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:G19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GPER1 G protein-coupled estrogen receptor 1 2.65233
SNAP25 synaptosomal-associated protein, 25kDa 2.55259
TBPL1 TBP-like 1 2.51
TXNRD1 thioredoxin reductase 1 2.02454
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.01269

decreased expression

Symbol Name Standardized Value
TUBA4A tubulin, alpha 4a -4.32803
CTNND1 catenin (cadherin-associated protein), delta 1 -3.5056
CD44 CD44 molecule (Indian blood group) -2.54518
MSN moesin -2.51446
C2CD5 C2 calcium-dependent domain containing 5 -2.41157
RBM34 RNA binding motif protein 34 -2.21619
KDM3A lysine (K)-specific demethylase 3A -2.20736
IGFBP7 insulin-like growth factor binding protein 7 -2.19364
PSIP1 PC4 and SFRS1 interacting protein 1 -2.17826