CRCGN016_MCF10A.TP53.M_24H:G20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-amino-5-nitrothiazole 32.1 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:G20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RPL39L ribosomal protein L39-like 5.28881
SPAG4 sperm associated antigen 4 4.44113
ANO10 anoctamin 10 3.89262
TIAM1 T-cell lymphoma invasion and metastasis 1 3.23537
GPATCH8 G patch domain containing 8 2.94342
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.56772
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.39665
FTO fat mass and obesity associated 2.27434
GET1 guided entry of tail-anchored proteins factor 1 2.12281
HADH hydroxyacyl-CoA dehydrogenase 2.01634

decreased expression

Symbol Name Standardized Value
GNAS GNAS complex locus -4.01204
TSPAN4 tetraspanin 4 -3.99952
GDF15 growth differentiation factor 15 -3.92159
GADD45B growth arrest and DNA-damage-inducible, beta -3.79328
CD58 CD58 molecule -3.6661
ATP5F1E ATP synthase F1 subunit epsilon -2.66212
MT2A metallothionein 2A -2.48614
STXBP2 syntaxin binding protein 2 -2.37738
CETP cholesteryl ester transfer protein, plasma -2.10527
MTERF3 mitochondrial transcription termination factor 3 -2.08867