CRCGN016_MCF10A.TP53.M_24H:G22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,6-dimethylaniline 98.21 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:G22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZNF586 zinc finger protein 586 3.68185
MAP7 microtubule-associated protein 7 3.58279
CDK19 cyclin-dependent kinase 19 2.79293
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.52887
ZNF544 zinc finger protein 544 2.36837
ZNF134 zinc finger protein 134 2.36704
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.30573
CCL2 chemokine (C-C motif) ligand 2 2.29703
STX1A syntaxin 1A (brain) 2.24259
QDPR quinoid dihydropteridine reductase 2.0637

decreased expression

Symbol Name Standardized Value
TNIP1 TNFAIP3 interacting protein 1 -6.18945
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.60338
TEX10 testis expressed 10 -3.38176
HAT1 histone acetyltransferase 1 -3.31992
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.77453
FPGS folylpolyglutamate synthase -2.71244