CRCGN016_MCF10A.TP53.M_24H:G23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,6-dimethylaniline 32.74 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:G23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 3.54708
HYOU1 hypoxia up-regulated 1 3.40496
LAGE3 L antigen family, member 3 3.27171
ZNF586 zinc finger protein 586 3.19391
TSPAN6 tetraspanin 6 2.48321
VBP1 von Hippel-Lindau binding protein 1 2.38015
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.27789
H2BC21 H2B clustered histone 21 2.13934
ISOC1 isochorismatase domain containing 1 2.002

decreased expression

Symbol Name Standardized Value
STX1A syntaxin 1A (brain) -3.97365
PCNA proliferating cell nuclear antigen -2.84853
MTERF3 mitochondrial transcription termination factor 3 -2.53414
RNF167 ring finger protein 167 -2.50376
BPHL biphenyl hydrolase-like (serine hydrolase) -2.36477
HSPA1A heat shock 70kDa protein 1A -2.11419
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.10593