CRCGN016_MCF10A.TP53.M_24H:G24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,6-dimethylaniline 10.91 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:G24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STK10 serine/threonine kinase 10 4.98487
CCNF cyclin F 2.8853
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 2.47905
BMP4 bone morphogenetic protein 4 2.38551
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.31804
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.03244
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 2.02712

decreased expression

Symbol Name Standardized Value
YME1L1 YME1-like 1 ATPase -4.65689
BASP1 brain abundant, membrane attached signal protein 1 -4.35046
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -3.41931
SLC35F2 solute carrier family 35, member F2 -3.27837
MT1X metallothionein 1X -2.91619
HSPA1A heat shock 70kDa protein 1A -2.88696
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.57852
ABI1 abl-interactor 1 -2.49569
MAP7 microtubule-associated protein 7 -2.44058
MPC2 mitochondrial pyruvate carrier 2 -2.27291
WASHC4 WASH complex subunit 4 -2.14191
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.11446
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.0512
KIF14 kinesin family member 14 -2.02251