| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | p-nitroaniline 100.46 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
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100 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:H04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 3.67865 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.6348 |
| MCOLN1 | mucolipin 1 | 3.61281 |
| ZNF586 | zinc finger protein 586 | 3.58736 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 3.42545 |
| MAMLD1 | mastermind-like domain containing 1 | 3.18464 |
| CADM1 | cell adhesion molecule 1 | 2.97758 |
| E2F2 | E2F transcription factor 2 | 2.82522 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | 2.5362 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.53303 |
| TRIB3 | tribbles pseudokinase 3 | 2.51829 |
| CHN1 | chimerin 1 | 2.47686 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 2.43068 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 | 2.41894 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 | 2.39869 |
| PPOX | protoporphyrinogen oxidase | 2.35327 |
| H2BC12 | H2B clustered histone 12 | 2.34752 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 2.30833 |
| WBP2 | WW domain binding protein 2 | 2.29061 |
| ALDOC | aldolase C, fructose-bisphosphate | 2.28706 |
| DHX16 | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 2.27761 |
| MOGS | mannosyl-oligosaccharide glucosidase | 2.27653 |
| H2AC7 | H2A clustered histone 7 | 2.26618 |
| THBS3 | thrombospondin 3 | 2.25892 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 2.2492 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 2.2224 |
| THOC6 | THO complex 6 | 2.21883 |
| ZNF671 | zinc finger protein 671 | 2.20271 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 2.19148 |
| CCL7 | chemokine (C-C motif) ligand 7 | 2.17462 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) | 2.17065 |
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 | 2.16554 |
| RPAP1 | RNA polymerase II associated protein 1 | 2.11501 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) | 2.10731 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 | 2.10233 |
| MSH5 | mutS homolog 5 | 2.08582 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | 2.07507 |
| MARCHF8 | membrane associated ring-CH-type finger 8 | 2.07504 |
| PCDHGA3 | protocadherin gamma subfamily A, 3 | 2.07475 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 2.07348 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 2.07255 |
| REC8 | REC8 meiotic recombination protein | 2.07202 |
| CEP170B | centrosomal protein 170B | 2.06873 |
| GDAP1L1 | ganglioside induced differentiation associated protein 1-like 1 | 2.05887 |
| WDR13 | WD repeat domain 13 | 2.05749 |
| CPTP | ceramide-1-phosphate transfer protein | 2.05108 |
| ZNF358 | zinc finger protein 358 | 2.04862 |
| PCDHB6 | protocadherin beta 6 | 2.04721 |
| OSBPL10 | oxysterol binding protein-like 10 | 2.03159 |
| ACP5 | acid phosphatase 5, tartrate resistant | 2.02115 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HAT1 | histone acetyltransferase 1 | -4.86109 |
| HSPA1A | heat shock 70kDa protein 1A | -4.14733 |
| BAG3 | BCL2-associated athanogene 3 | -4.14059 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -4.03571 |
| LDHD | lactate dehydrogenase D | -3.85909 |
| PIH1D1 | PIH1 domain containing 1 | -3.85774 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -3.85225 |
| ANXA2 | annexin A2 | -3.7764 |
| HEATR1 | HEAT repeat containing 1 | -3.73596 |
| TOR1A | torsin family 1, member A (torsin A) | -3.43273 |
| COTL1 | coactosin-like F-actin binding protein 1 | -3.17187 |
| CCNB2 | cyclin B2 | -3.17114 |
| BCAP29 | B-cell receptor-associated protein 29 | -3.05419 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.98726 |
| HSPA8 | heat shock 70kDa protein 8 | -2.98123 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -2.91781 |
| TMEM168 | transmembrane protein 168 | -2.854 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.72251 |
| TUBB6 | tubulin, beta 6 class V | -2.65351 |
| EFHD2 | EF-hand domain family, member D2 | -2.62005 |
| TIPIN | TIMELESS interacting protein | -2.61162 |
| GLTP | glycolipid transfer protein | -2.58006 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -2.54013 |
| PPP1R8 | protein phosphatase 1, regulatory subunit 8 | -2.4814 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -2.47247 |
| PCNA | proliferating cell nuclear antigen | -2.42137 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -2.41852 |
| FASTKD5 | FAST kinase domains 5 | -2.32114 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | -2.24317 |
| CDC42SE1 | CDC42 small effector 1 | -2.23439 |
| OBI1 | ORC ubiquitin ligase 1 | -2.23318 |
| TOR1AIP2 | torsin A interacting protein 2 | -2.21098 |
| POLR1G | RNA polymerase I subunit G | -2.20321 |
| TMEM109 | transmembrane protein 109 | -2.19613 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -2.19101 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.14987 |
| STMN1 | stathmin 1 | -2.14271 |
| COG5 | component of oligomeric golgi complex 5 | -2.13881 |
| CTSZ | cathepsin Z | -2.12915 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -2.12453 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component | -2.1149 |
| CDCA4 | cell division cycle associated 4 | -2.10673 |
| MCM3 | minichromosome maintenance complex component 3 | -2.10516 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 | -2.10284 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.09496 |
| TRIM32 | tripartite motif containing 32 | -2.06267 |
| SLC35F2 | solute carrier family 35, member F2 | -2.0544 |
| DCK | deoxycytidine kinase | -2.05295 |
| MSN | moesin | -2.0442 |
| EMID1 | EMI domain containing 1 | -2.00761 |