CRCGN016_MCF10A.TP53.M_24H:H05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p-nitroaniline 33.49 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:H05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.86359
AGR2 anterior gradient 2 3.41657
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 3.26083
BZW2 basic leucine zipper and W2 domains 2 2.60225
PEX12 peroxisomal biogenesis factor 12 2.47907
CCNA1 cyclin A1 2.39986
ACAA1 acetyl-CoA acyltransferase 1 2.32569
TRIM24 tripartite motif containing 24 2.17063

decreased expression

Symbol Name Standardized Value
PGAM4 phosphoglycerate mutase family member 4 -4.19885
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.76936
ACOT9 acyl-CoA thioesterase 9 -3.62385
PCCB propionyl CoA carboxylase, beta polypeptide -3.55595
CCDC86 coiled-coil domain containing 86 -3.46816
CCNB1 cyclin B1 -3.43996
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -3.41801
CDC25B cell division cycle 25B -3.38283
CHMP4B charged multivesicular body protein 4B -3.3119
TNIP1 TNFAIP3 interacting protein 1 -3.28278
MAPK13 mitogen-activated protein kinase 13 -2.71931
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.54123
DNM1L dynamin 1-like -2.51171
MTERF3 mitochondrial transcription termination factor 3 -2.41532
CAPN2 calpain 2, (m/II) large subunit -2.36629
MX2 MX dynamin-like GTPase 2 -2.17374
SINHCAF SIN3-HDAC complex associated factor -2.13285
FXYD6-FXYD2 FXYD6-FXYD2 readthrough -2.10252
TRAPPC6A trafficking protein particle complex 6A -2.05442
CCL23 chemokine (C-C motif) ligand 23 -2.03403
KRT14 keratin 14, type I -2.01626