CRCGN016_MCF10A.TP53.M_24H:H12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description diallyl phthalate 11.05 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:H12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCL2 chemokine (C-X-C motif) ligand 2 4.11371
TLR4 toll-like receptor 4 3.78561
HBB hemoglobin, beta 3.3164
ACAA1 acetyl-CoA acyltransferase 1 2.60508
SATB1 SATB homeobox 1 2.46528
ESRP2 epithelial splicing regulatory protein 2 2.27625
METRN meteorin, glial cell differentiation regulator 2.23189
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.17848
MEST mesoderm specific transcript 2.14284
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.11976
UBA3 ubiquitin-like modifier activating enzyme 3 2.11639
KDM5D lysine (K)-specific demethylase 5D 2.11628
CD1D CD1d molecule 2.09199
MECR mitochondrial trans-2-enoyl-CoA reductase 2.08977
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 2.05263
MARCHF1 membrane associated ring-CH-type finger 1 2.01873

decreased expression

Symbol Name Standardized Value
UFM1 ubiquitin-fold modifier 1 -4.38643
PMM2 phosphomannomutase 2 -4.26053
PUF60 poly-U binding splicing factor 60KDa -4.19147
ADI1 acireductone dioxygenase 1 -4.07095
CCDC86 coiled-coil domain containing 86 -4.05418
KIF14 kinesin family member 14 -3.90601
CHMP4B charged multivesicular body protein 4B -3.82134
PCNA proliferating cell nuclear antigen -3.82018
PRPF4 pre-mRNA processing factor 4 -3.6233
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.50098
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.26735
HOXA5 homeobox A5 -3.12515
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.50858
MSN moesin -2.48179
FKBP1C FK506 binding protein 1C -2.36834
TBCB tubulin folding cofactor B -2.34307
ZNF146 zinc finger protein 146 -2.338
TMEM230 transmembrane protein 230 -2.16626
KRT14 keratin 14, type I -2.16408
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa -2.07981
KDM5C lysine (K)-specific demethylase 5C -2.06398
PFN1 profilin 1 -2.0554
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -2.05002