CRCGN016_MCF10A.TP53.M_24H:H13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description barium chloride dihydrate 101.98 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:H13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
BMP4 bone morphogenetic protein 4 4.81604
CIAO3 cytosolic iron-sulfur assembly component 3 4.7959
TSEN2 TSEN2 tRNA splicing endonuclease subunit 4.73599
GPER1 G protein-coupled estrogen receptor 1 4.60872
KDM5D lysine (K)-specific demethylase 5D 2.85358
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.5697
H1-0 H1.0 linker histone 2.52725
KLHL21 kelch-like family member 21 2.51822
HBA1 hemoglobin, alpha 1 2.50114
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.41312
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.39745
TPD52L2 tumor protein D52-like 2 2.26921
CCNA1 cyclin A1 2.20054
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.15537
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.1529
TERF2 telomeric repeat binding factor 2 2.11476
CKAP2 cytoskeleton associated protein 2 2.04307
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 2.03011

decreased expression

Symbol Name Standardized Value
CTNND1 catenin (cadherin-associated protein), delta 1 -4.00891
EIF5 eukaryotic translation initiation factor 5 -3.0254
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.85985
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.7182
TRIB3 tribbles pseudokinase 3 -2.66916
PFN1 profilin 1 -2.48645
SMC1A structural maintenance of chromosomes 1A -2.43162
MSN moesin -2.33185
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.31753
KDM5C lysine (K)-specific demethylase 5C -2.30278
PARP12 poly (ADP-ribose) polymerase family, member 12 -2.23521
SST somatostatin -2.18755
SIAH1 siah E3 ubiquitin protein ligase 1 -2.15585
HMGN3 high mobility group nucleosomal binding domain 3 -2.13769
ATP11B ATPase, class VI, type 11B -2.12125
ZNF587 zinc finger protein 587 -2.09523
KDM6A lysine (K)-specific demethylase 6A -2.08271
ZNF26 zinc finger protein 26 -2.08115