CRCGN016_MCF10A.TP53.M_24H:H20 Gene Set
Genes
36 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:H20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HMOX1
|
heme oxygenase 1
|
4.48548
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.14242
|
|
KDM5D
|
lysine (K)-specific demethylase 5D
|
3.89842
|
|
KCTD5
|
potassium channel tetramerization domain containing 5
|
3.10842
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
2.98047
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.85716
|
|
EIF1AY
|
eukaryotic translation initiation factor 1A, Y-linked
|
2.75967
|
|
USP7
|
ubiquitin specific peptidase 7 (herpes virus-associated)
|
2.70351
|
|
SLC1A4
|
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
|
2.56045
|
|
SPAG4
|
sperm associated antigen 4
|
2.46613
|
|
MMP1
|
matrix metallopeptidase 1
|
2.30893
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
2.06312
|
|
LOXL1
|
lysyl oxidase-like 1
|
2.06114
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-4.60042
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-4.36772
|
|
KIF14
|
kinesin family member 14
|
-4.29608
|
|
CCNB1
|
cyclin B1
|
-4.15506
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.94335
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.83592
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
-3.25645
|
|
SMC1A
|
structural maintenance of chromosomes 1A
|
-3.23106
|
|
LYPLA1
|
lysophospholipase I
|
-3.09511
|
|
TLK2
|
tousled-like kinase 2
|
-2.90501
|
|
DCTD
|
dCMP deaminase
|
-2.51715
|
|
PLK1
|
polo-like kinase 1
|
-2.42677
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.41416
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.38487
|
|
KDM5C
|
lysine (K)-specific demethylase 5C
|
-2.34421
|
|
PLSCR4
|
phospholipid scramblase 4
|
-2.31769
|
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
-2.16558
|
|
LOC124905557
|
eukaryotic translation initiation factor 1A, X-chromosomal
|
-2.14842
|
|
TIMP1
|
TIMP metallopeptidase inhibitor 1
|
-2.12383
|
|
SDCBP
|
syndecan binding protein (syntenin)
|
-2.10175
|
|
RUSC1
|
RUN and SH3 domain containing 1
|
-2.08496
|
|
ECT2
|
epithelial cell transforming 2
|
-2.03818
|
|
OAT
|
ornithine aminotransferase
|
-2.0292
|
