| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | estriol 11.33 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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74 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:H21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 5.16804 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.67065 |
| ABHD6 | abhydrolase domain containing 6 | 4.6532 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 4.22236 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 3.5204 |
| FADS2 | fatty acid desaturase 2 | 3.50388 |
| STK10 | serine/threonine kinase 10 | 3.446 |
| ACLY | ATP citrate lyase | 3.24618 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 3.16314 |
| CETN3 | centrin, EF-hand protein, 3 | 2.7612 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.75292 |
| MTA1 | metastasis associated 1 | 2.57662 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 2.57013 |
| CCDC85B | coiled-coil domain containing 85B | 2.39252 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 | 2.37319 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) | 2.29875 |
| DENND2D | DENN/MADD domain containing 2D | 2.27483 |
| GAS6 | growth arrest-specific 6 | 2.14238 |
| LGALS7B | lectin, galactoside-binding, soluble, 7B | 2.14018 |
| SPAG4 | sperm associated antigen 4 | 2.12389 |
| MVD | mevalonate (diphospho) decarboxylase | 2.09646 |
| ZNF282 | zinc finger protein 282 | 2.08968 |
| PSORS1C2 | psoriasis susceptibility 1 candidate 2 | 2.08361 |
| KRTAP5-2 | keratin associated protein 5-2 | 2.06968 |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 2.05404 |
| KCNK7 | potassium channel, two pore domain subfamily K, member 7 | 2.05219 |
| DHCR7 | 7-dehydrocholesterol reductase | 2.05142 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 2.04251 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | 2.03564 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 2.02833 |
| PDCD1 | programmed cell death 1 | 2.01562 |
| EDN2 | endothelin 2 | 2.01237 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) | 2.00748 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DYNLT3 | dynein, light chain, Tctex-type 3 | -5.47684 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -5.20191 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.96942 |
| COG7 | component of oligomeric golgi complex 7 | -4.9519 |
| ENOPH1 | enolase-phosphatase 1 | -4.89908 |
| CCNB1 | cyclin B1 | -4.87769 |
| ATF5 | activating transcription factor 5 | -4.43012 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -3.74965 |
| ANXA2 | annexin A2 | -3.71117 |
| TBCB | tubulin folding cofactor B | -3.6791 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -3.38545 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -3.2284 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -3.06236 |
| HSPA1A | heat shock 70kDa protein 1A | -2.81726 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -2.7327 |
| MT2A | metallothionein 2A | -2.69998 |
| ANKRD10 | ankyrin repeat domain 10 | -2.61935 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | -2.60528 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | -2.57015 |
| UBFD1 | ubiquitin family domain containing 1 | -2.47624 |
| RGS2 | regulator of G-protein signaling 2 | -2.42914 |
| RBM42 | RNA binding motif protein 42 | -2.32043 |
| ZNF652 | zinc finger protein 652 | -2.28027 |
| HHEX | hematopoietically expressed homeobox | -2.26626 |
| SDHAF1 | succinate dehydrogenase complex assembly factor 1 | -2.23608 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | -2.21714 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 | -2.19666 |
| GPATCH1 | G patch domain containing 1 | -2.18746 |
| SELE | selectin E | -2.16915 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -2.16306 |
| TMEM147 | transmembrane protein 147 | -2.15835 |
| NPIPA6 | nuclear pore complex interacting protein family, member A6 | -2.15333 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 | -2.15322 |
| TEP1 | telomerase-associated protein 1 | -2.14612 |
| MT1X | metallothionein 1X | -2.11877 |
| HIRA | histone cell cycle regulator | -2.10923 |
| ETNK1 | ethanolamine kinase 1 | -2.08375 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -2.08109 |
| CAPNS1 | calpain, small subunit 1 | -2.06788 |
| GDF15 | growth differentiation factor 15 | -2.03498 |
| CSTA | cystatin A (stefin A) | -2.00508 |
