CRCGN016_MCF10A.TP53.M_24H:H24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,2-bis(bromomethyl)-1,3-pro?panediol, technical grade 11.34 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

11 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:H24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KIF5C kinesin family member 5C 4.21896
NOTCH1 notch 1 4.13789
EXOSC4 exosome component 4 3.56865
KAT6B K(lysine) acetyltransferase 6B 2.16352
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.07737
IGHMBP2 immunoglobulin mu binding protein 2 2.07526

decreased expression

Symbol Name Standardized Value
GRWD1 glutamate-rich WD repeat containing 1 -3.76248
SMC1A structural maintenance of chromosomes 1A -2.49258
TEX10 testis expressed 10 -2.35324
KDM5C lysine (K)-specific demethylase 5C -2.26977
MTFR1 mitochondrial fission regulator 1 -2.00862