CRCGN016_MCF10A.TP53.M_24H:I01 Gene Set
Genes
27 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
3.51866
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.52778
|
|
SPAG4
|
sperm associated antigen 4
|
2.4793
|
|
SATB1
|
SATB homeobox 1
|
2.40302
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
2.38186
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
2.13009
|
|
GTF2E2
|
general transcription factor IIE, polypeptide 2, beta 34kDa
|
2.07744
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
2.02069
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MSMO1
|
methylsterol monooxygenase 1
|
-5.90958
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.65978
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-4.01907
|
|
STXBP2
|
syntaxin binding protein 2
|
-3.49653
|
|
DECR1
|
2,4-dienoyl CoA reductase 1, mitochondrial
|
-2.78518
|
|
DCK
|
deoxycytidine kinase
|
-2.77226
|
|
MVD
|
mevalonate (diphospho) decarboxylase
|
-2.48452
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
-2.44993
|
|
INSIG1
|
insulin induced gene 1
|
-2.35623
|
|
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6
|
-2.2658
|
|
IDI1
|
isopentenyl-diphosphate delta isomerase 1
|
-2.24207
|
|
SQLE
|
squalene epoxidase
|
-2.13946
|
|
SOAT2
|
sterol O-acyltransferase 2
|
-2.12341
|
|
TCEA2
|
transcription elongation factor A (SII), 2
|
-2.08832
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
-2.05564
|
|
ECH1
|
enoyl CoA hydratase 1, peroxisomal
|
-2.05524
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
-2.0474
|
|
OCLN
|
occludin
|
-2.03849
|
|
OSTF1
|
osteoclast stimulating factor 1
|
-2.01592
|
