CRCGN016_MCF10A.TP53.M_24H:I02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methoxychlor 33.66 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

37 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZMIZ1 zinc finger, MIZ-type containing 1 4.00489
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 3.76404
CCDC92 coiled-coil domain containing 92 3.48252
PRR7 proline rich 7 (synaptic) 3.46222
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.2727
KDM5D lysine (K)-specific demethylase 5D 3.04751
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 3.03615
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.52469
CADM1 cell adhesion molecule 1 2.50823
WASF3 WAS protein family, member 3 2.38857
DENND2D DENN/MADD domain containing 2D 2.30952
MTA2 metastasis associated 1 family, member 2 2.07109
ZNF768 zinc finger protein 768 2.07019
MDM4 MDM4, p53 regulator 2.05192
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 2.04627
TEDC2 tubulin epsilon and delta complex 2 2.00862

decreased expression

Symbol Name Standardized Value
BAG3 BCL2-associated athanogene 3 -4.41866
MSMO1 methylsterol monooxygenase 1 -3.97979
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.58632
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.52772
NUP85 nucleoporin 85kDa -3.37259
MAPK13 mitogen-activated protein kinase 13 -3.24789
DCK deoxycytidine kinase -3.23988
CCNB1 cyclin B1 -3.07251
BASP1 brain abundant, membrane attached signal protein 1 -2.94703
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.9026
ECH1 enoyl CoA hydratase 1, peroxisomal -2.74328
INSIG1 insulin induced gene 1 -2.71839
RGS2 regulator of G-protein signaling 2 -2.69192
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -2.61321
SH3D19 SH3 domain containing 19 -2.27226
SMC1A structural maintenance of chromosomes 1A -2.2519
JPT1 Jupiter microtubule associated homolog 1 -2.20908
ALDOC aldolase C, fructose-bisphosphate -2.17006
SERF1A small EDRK-rich factor 1A (telomeric) -2.07983
STXBP1 syntaxin binding protein 1 -2.0717
PUDP pseudouridine 5'-phosphatase -2.03447