CRCGN016_MCF10A.TP53.M_24H:I03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methoxychlor 11.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GPER1 G protein-coupled estrogen receptor 1 4.05254
BDH1 3-hydroxybutyrate dehydrogenase, type 1 3.43683
SNX11 sorting nexin 11 3.40811
TIAM1 T-cell lymphoma invasion and metastasis 1 2.9205
AMDHD2 amidohydrolase domain containing 2 2.88713
CCNA1 cyclin A1 2.88141
RPL39L ribosomal protein L39-like 2.84084
ACAA1 acetyl-CoA acyltransferase 1 2.83172
C2CD2 C2 calcium-dependent domain containing 2 2.73062
MCOLN1 mucolipin 1 2.67521
SOCS2 suppressor of cytokine signaling 2 2.22775
DUSP2 dual specificity phosphatase 2 2.1871
H2BC21 H2B clustered histone 21 2.12905
EMX2 empty spiracles homeobox 2 2.09722
SKIC8 SKI8 subunit of superkiller complex 2.00858

decreased expression

Symbol Name Standardized Value
RNF167 ring finger protein 167 -3.50789
CCNB1 cyclin B1 -3.46624
CAB39 calcium binding protein 39 -3.45319
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.99671
MSN moesin -2.85439
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.74427
UFM1 ubiquitin-fold modifier 1 -2.59046
PFN1 profilin 1 -2.43696
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.41953
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 -2.36044
HSPA8 heat shock 70kDa protein 8 -2.32356
TEX10 testis expressed 10 -2.28159
SLC25A46 solute carrier family 25, member 46 -2.13175
TRIM36 tripartite motif containing 36 -2.11091
ISOC1 isochorismatase domain containing 1 -2.07328
KIZ kizuna centrosomal protein -2.00475