CRCGN016_MCF10A.TP53.M_24H:I04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description c.i. acid orange 10 101.47 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.09778
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.09699
OXSR1 oxidative stress responsive 1 2.69609
EVL Enah/Vasp-like 2.47021
EDN1 endothelin 1 2.28789

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -3.30168
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.01259
RALGDS ral guanine nucleotide dissociation stimulator -2.88183
YME1L1 YME1-like 1 ATPase -2.81425
CBR3 carbonyl reductase 3 -2.81417
MSN moesin -2.73518
KDM3A lysine (K)-specific demethylase 3A -2.66031
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.64825
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.50249
TEX10 testis expressed 10 -2.36307
HOXA5 homeobox A5 -2.13703
USP20 ubiquitin specific peptidase 20 -2.01698