CRCGN016_MCF10A.TP53.M_24H:I06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description c.i. acid orange 10 11.27 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

13 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 4.01938
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.85878
SSBP2 single-stranded DNA binding protein 2 3.83402
TBX2 T-box 2 3.6597
TIAM1 T-cell lymphoma invasion and metastasis 1 2.63579
CETN3 centrin, EF-hand protein, 3 2.47462
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.32813

decreased expression

Symbol Name Standardized Value
RPIA ribose 5-phosphate isomerase A -4.30776
TUBB6 tubulin, beta 6 class V -4.20242
HEATR1 HEAT repeat containing 1 -3.79876
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.63698
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.32774
BASP1 brain abundant, membrane attached signal protein 1 -2.09503