CRCGN016_MCF10A.TP53.M_24H:I07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sulfafurazole 100.97 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 4.26936
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.74681
CCP110 centriolar coiled coil protein 110kDa 3.74032
AGR2 anterior gradient 2 3.58965
SSBP2 single-stranded DNA binding protein 2 3.15882
SNAP25 synaptosomal-associated protein, 25kDa 3.09312
WIF1 WNT inhibitory factor 1 2.56895
FKBP14 FK506 binding protein 14, 22 kDa 2.29477
CEP57 centrosomal protein 57kDa 2.24868
PDLIM1 PDZ and LIM domain 1 2.15455
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.03951
CHN1 chimerin 1 2.03222

decreased expression

Symbol Name Standardized Value
PUF60 poly-U binding splicing factor 60KDa -7.20111
WASHC4 WASH complex subunit 4 -3.26646
NLRP4 NLR family, pyrin domain containing 4 -3.07455
TRAPPC6A trafficking protein particle complex 6A -3.00513
SCRIB scribbled planar cell polarity protein -2.89913
KIF14 kinesin family member 14 -2.30803
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.21369
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.20466
TRIB3 tribbles pseudokinase 3 -2.15754
ZC3H3 zinc finger CCCH-type containing 3 -2.15715
NUSAP1 nucleolar and spindle associated protein 1 -2.12656
JRK Jrk homolog (mouse) -2.03933
GSDMD gasdermin D -2.00956