| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sulfafurazole 33.66 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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50 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 | 5.55955 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 5.24452 |
| WFS1 | Wolfram syndrome 1 (wolframin) | 5.1324 |
| HBA1 | hemoglobin, alpha 1 | 5.0 |
| KEAP1 | kelch-like ECH-associated protein 1 | 4.38375 |
| DENND2D | DENN/MADD domain containing 2D | 3.87565 |
| HBB | hemoglobin, beta | 3.55468 |
| WIF1 | WNT inhibitory factor 1 | 3.38375 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.05433 |
| MTA2 | metastasis associated 1 family, member 2 | 3.0532 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.62135 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 2.56565 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 2.49085 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 2.43125 |
| WDR76 | WD repeat domain 76 | 2.3355 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase | 2.33185 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 2.30497 |
| SUMO4 | small ubiquitin-like modifier 4 | 2.2433 |
| MDM4 | MDM4, p53 regulator | 2.2311 |
| OSTF1 | osteoclast stimulating factor 1 | 2.1726 |
| ORC3 | origin recognition complex, subunit 3 | 2.16845 |
| IFI6 | interferon, alpha-inducible protein 6 | 2.1567 |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | 2.1338 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 2.12192 |
| ZNF292 | zinc finger protein 292 | 2.089 |
| PRPF39 | pre-mRNA processing factor 39 | 2.0683 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 2.06532 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 | 2.05315 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 2.04535 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TCTA | T-cell leukemia translocation altered | -4.95555 |
| KRT14 | keratin 14, type I | -4.8469 |
| WASHC4 | WASH complex subunit 4 | -4.47707 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -4.04633 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -4.0188 |
| PRCP | prolylcarboxypeptidase (angiotensinase C) | -3.69105 |
| NISCH | nischarin | -3.6545 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -2.92972 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.9093 |
| NLRP4 | NLR family, pyrin domain containing 4 | -2.813 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -2.64815 |
| RPAP1 | RNA polymerase II associated protein 1 | -2.41295 |
| LIN7A | lin-7 homolog A (C. elegans) | -2.3917 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 | -2.37805 |
| GDF15 | growth differentiation factor 15 | -2.3615 |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) | -2.3467 |
| STK25 | serine/threonine kinase 25 | -2.2209 |
| OSBPL8 | oxysterol binding protein-like 8 | -2.15878 |
| COTL1 | coactosin-like F-actin binding protein 1 | -2.1388 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G | -2.13625 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.12755 |
