CRCGN016_MCF10A.TP53.M_24H:I09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sulfafurazole 11.22 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COMP cartilage oligomeric matrix protein 3.81507
NOTCH1 notch 1 3.79333
LGMN legumain 3.35051
SNAP25 synaptosomal-associated protein, 25kDa 3.15613
ACAA1 acetyl-CoA acyltransferase 1 3.00524
CNRIP1 cannabinoid receptor interacting protein 1 2.63872
CBR4 carbonyl reductase 4 2.43571
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.34128
GET1 guided entry of tail-anchored proteins factor 1 2.12906
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 2.12709
WIF1 WNT inhibitory factor 1 2.10852
CCP110 centriolar coiled coil protein 110kDa 2.07036

decreased expression

Symbol Name Standardized Value
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -5.1646
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -5.05135
HMG20B high mobility group 20B -4.92899
CCDC86 coiled-coil domain containing 86 -4.90794
TLK2 tousled-like kinase 2 -2.74151
TMEM260 transmembrane protein 260 -2.69825
PIH1D1 PIH1 domain containing 1 -2.35333
GREB1L growth regulation by estrogen in breast cancer-like -2.17813
GDF15 growth differentiation factor 15 -2.17092
CUTA cutA divalent cation tolerance homolog (E. coli) -2.09362
CLDN15 claudin 15 -2.0163