CRCGN016_MCF10A.TP53.M_24H:I16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ditiocarb-sodium-trihydrate 99.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
VAV3 vav 3 guanine nucleotide exchange factor 3.36017
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.3481
EVL Enah/Vasp-like 2.92161
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.54529
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.38052
CCNF cyclin F 2.30716
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.19568

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -3.38628
CCNB1 cyclin B1 -3.37555
HMG20B high mobility group 20B -3.07221
DYNLT3 dynein, light chain, Tctex-type 3 -2.84802
PCCB propionyl CoA carboxylase, beta polypeptide -2.50707
RBM34 RNA binding motif protein 34 -2.31466
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.25494
COTL1 coactosin-like F-actin binding protein 1 -2.17336
VDAC1 voltage-dependent anion channel 1 -2.04613