CRCGN016_MCF10A.TP53.M_24H:I18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ditiocarb-sodium-trihydrate 11.03 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

24 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 3.28023
ARID5B AT rich interactive domain 5B (MRF1-like) 2.6855
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.57353
BACE2 beta-site APP-cleaving enzyme 2 2.51926
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.483
TBC1D31 TBC1 domain family, member 31 2.04855
APOE apolipoprotein E 2.03086

decreased expression

Symbol Name Standardized Value
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -6.71961
TBCB tubulin folding cofactor B -3.30733
TMEM147 transmembrane protein 147 -3.25418
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -3.22763
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -3.16116
THAP11 THAP domain containing 11 -3.15869
TLK2 tousled-like kinase 2 -3.05941
COG2 component of oligomeric golgi complex 2 -2.93008
VTI1B vesicle transport through interaction with t-SNAREs 1B -2.68935
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -2.53004
GPATCH1 G patch domain containing 1 -2.46725
CA8 carbonic anhydrase VIII -2.3281
LIN37 lin-37 DREAM MuvB core complex component -2.30622
PSENEN presenilin enhancer gamma secretase subunit -2.28827
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.20429
ZNF146 zinc finger protein 146 -2.13248
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -2.04139