CRCGN016_MCF10A.TP53.M_24H:I19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-dichlorobenzene 100.8 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

8 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD4 abhydrolase domain containing 4 4.03517
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 2.23759
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.07475
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.01768

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -3.81294
PCNA proliferating cell nuclear antigen -3.67623
TIMP1 TIMP metallopeptidase inhibitor 1 -2.31755
MT2A metallothionein 2A -2.22288