CRCGN016_MCF10A.TP53.M_24H:I21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-dichlorobenzene 11.2 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CLNS1A chloride channel, nucleotide-sensitive, 1A 3.79462
STAP2 signal transducing adaptor family member 2 3.35484
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.18523
CNRIP1 cannabinoid receptor interacting protein 1 2.99368
WFS1 Wolfram syndrome 1 (wolframin) 2.91898
MAP7 microtubule-associated protein 7 2.75667
FGFR4 fibroblast growth factor receptor 4 2.33856
TSPAN6 tetraspanin 6 2.14688
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.14388
THAP12 THAP domain containing 12 2.10531
CHEK2 checkpoint kinase 2 2.10297
POPDC3 popeye domain containing 3 2.00268

decreased expression

Symbol Name Standardized Value
PMM2 phosphomannomutase 2 -3.63907
WASHC4 WASH complex subunit 4 -3.00023
LAP3 leucine aminopeptidase 3 -2.86738
MRPS2 mitochondrial ribosomal protein S2 -2.80781
TNIP1 TNFAIP3 interacting protein 1 -2.73363
CAPN2 calpain 2, (m/II) large subunit -2.18593