| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | succinic anhydride 101.47 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PNKP | polynucleotide kinase 3'-phosphatase | 5.28898 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 5.19355 |
| MAMLD1 | mastermind-like domain containing 1 | 5.11916 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 4.67015 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 4.56931 |
| ERCC1 | excision repair cross-complementation group 1 | 3.18845 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.97307 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.94426 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 2.71435 |
| SATB1 | SATB homeobox 1 | 2.57398 |
| DPH2 | DPH2 homolog (S. cerevisiae) | 2.47096 |
| ZNF586 | zinc finger protein 586 | 2.43726 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | 2.35607 |
| ERCC2 | excision repair cross-complementation group 2 | 2.27592 |
| BAX | BCL2-associated X protein | 2.19342 |
| DNM2 | dynamin 2 | 2.12111 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 2.10176 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.09998 |
| YY1 | YY1 transcription factor | 2.0626 |
| COMP | cartilage oligomeric matrix protein | 2.05806 |
| FIBP | fibroblast growth factor (acidic) intracellular binding protein | 2.03247 |
| ZNF428 | zinc finger protein 428 | 2.00607 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -5.2152 |
| PYGL | phosphorylase, glycogen, liver | -5.07982 |
| TSPAN4 | tetraspanin 4 | -4.75996 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.73117 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -4.40246 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | -2.79841 |
| BCAP29 | B-cell receptor-associated protein 29 | -2.64949 |
| CHMP4B | charged multivesicular body protein 4B | -2.5056 |
| HMG20B | high mobility group 20B | -2.48195 |
| PIH1D1 | PIH1 domain containing 1 | -2.46625 |
| DUS4L | dihydrouridine synthase 4-like (S. cerevisiae) | -2.42652 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | -2.4143 |
| ZNF267 | zinc finger protein 267 | -2.40907 |
| A2M | alpha-2-macroglobulin | -2.39728 |
| EMC2 | ER membrane protein complex subunit 2 | -2.38515 |
| TMEM51 | transmembrane protein 51 | -2.30544 |
| CRYZL1 | crystallin, zeta (quinone reductase)-like 1 | -2.26301 |
| IFRD1 | interferon-related developmental regulator 1 | -2.22375 |
| MFAP4 | microfibrillar-associated protein 4 | -2.21422 |
| GDF15 | growth differentiation factor 15 | -2.19573 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -2.19075 |
| CRCT1 | cysteine-rich C-terminal 1 | -2.17006 |
| LILRA3 | leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 | -2.13257 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | -2.11648 |
| TMEM168 | transmembrane protein 168 | -2.09477 |
| GCC1 | GRIP and coiled-coil domain containing 1 | -2.07384 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -2.07046 |
| COTL1 | coactosin-like F-actin binding protein 1 | -2.03701 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | -2.03577 |
| TBK1 | TANK-binding kinase 1 | -2.03127 |
| LAMB1 | laminin, beta 1 | -2.01904 |
| HCAR3 | hydroxycarboxylic acid receptor 3 | -2.01023 |
| PLTP | phospholipid transfer protein | -2.00894 |
