CRCGN016_MCF10A.TP53.M_24H:I23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description succinic anhydride 33.82 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZNF586 zinc finger protein 586 3.80284
TLR4 toll-like receptor 4 3.06464
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.90641
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.73042
MELK maternal embryonic leucine zipper kinase 2.68104
KCTD12 potassium channel tetramerization domain containing 12 2.5261
BMP4 bone morphogenetic protein 4 2.33494
HCLS1 hematopoietic cell-specific Lyn substrate 1 2.29851
ZNF134 zinc finger protein 134 2.10197
NXPE3 neurexophilin and PC-esterase domain family, member 3 2.07193
PINLYP phospholipase A2 inhibitor and LY6/PLAUR domain containing 2.04974
ZNF551 zinc finger protein 551 2.03217
APOL6 apolipoprotein L, 6 2.01265

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -4.17866
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.91851
UFM1 ubiquitin-fold modifier 1 -3.32744
TEX10 testis expressed 10 -3.08102
ZDHHC6 zinc finger, DHHC-type containing 6 -3.0525
NPDC1 neural proliferation, differentiation and control, 1 -2.88254
DERA deoxyribose-phosphate aldolase (putative) -2.75929
VDAC1 voltage-dependent anion channel 1 -2.73787
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.52872
CLIC4 chloride intracellular channel 4 -2.40753
GNAS GNAS complex locus -2.29853
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.18857
TERF2 telomeric repeat binding factor 2 -2.11144
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -2.06524
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -2.04455
MAP7 microtubule-associated protein 7 -2.00189