CRCGN016_MCF10A.TP53.M_24H:I24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description succinic anhydride 11.27 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:I24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCP110 centriolar coiled coil protein 110kDa 4.67434
ZNF586 zinc finger protein 586 3.16269
CNRIP1 cannabinoid receptor interacting protein 1 3.08319
NOTCH1 notch 1 2.90282
TMEM50A transmembrane protein 50A 2.72847
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.45981
FGFR2 fibroblast growth factor receptor 2 2.24198
HYOU1 hypoxia up-regulated 1 2.22037
DOCK1 dedicator of cytokinesis 1 2.15177
CAPN1 calpain 1, (mu/I) large subunit 2.01005

decreased expression

Symbol Name Standardized Value
FASTKD5 FAST kinase domains 5 -4.1109
BID BH3 interacting domain death agonist -3.7373
THAP11 THAP domain containing 11 -3.39237
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.34522
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.20789
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.84457
CAB39 calcium binding protein 39 -2.51564
KDM3A lysine (K)-specific demethylase 3A -2.43145
MT1X metallothionein 1X -2.42707
IFRD2 interferon-related developmental regulator 2 -2.22265
TXNDC9 thioredoxin domain containing 9 -2.21678
PIPOX pipecolic acid oxidase -2.00487