CRCGN016_MCF10A.TP53.M_24H:J01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tiabendazole 101.47 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:J01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 4.42096
MEF2C myocyte enhancer factor 2C 3.91206
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 3.42684
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.27697
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.9261
H2BC21 H2B clustered histone 21 2.83046
MYBPH myosin binding protein H 2.23371
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.22803
CENPB centromere protein B, 80kDa 2.2004
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.19913
H2BC12 H2B clustered histone 12 2.05453
CCDC81 coiled-coil domain containing 81 2.01783
PMM2 phosphomannomutase 2 2.01675
CRELD2 cysteine-rich with EGF-like domains 2 2.00895

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -3.87634
KRT14 keratin 14, type I -3.30665
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.08224
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.89092
UFM1 ubiquitin-fold modifier 1 -2.89061
TUBB6 tubulin, beta 6 class V -2.82509
TRAPPC3 trafficking protein particle complex 3 -2.57428
MSN moesin -2.4838
IGFBP7 insulin-like growth factor binding protein 7 -2.45147
ISOC1 isochorismatase domain containing 1 -2.35617
PCCB propionyl CoA carboxylase, beta polypeptide -2.31693
CREB1 cAMP responsive element binding protein 1 -2.22591
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.07368