| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dioxane 102.99 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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86 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:J04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CNRIP1 | cannabinoid receptor interacting protein 1 | 5.65844 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 5.11446 |
| E2F2 | E2F transcription factor 2 | 4.63425 |
| WIF1 | WNT inhibitory factor 1 | 4.48089 |
| MAP7 | microtubule-associated protein 7 | 4.36164 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.18765 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.59914 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.40359 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 3.26387 |
| TMPRSS11D | transmembrane protease, serine 11D | 3.09898 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 3.01091 |
| KDM5D | lysine (K)-specific demethylase 5D | 2.99736 |
| DAD1 | defender against cell death 1 | 2.83414 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.78701 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 2.70833 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 | 2.66694 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | 2.61387 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 2.55404 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.47523 |
| CERK | ceramide kinase | 2.43781 |
| COPS7A | COP9 signalosome subunit 7A | 2.4164 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 2.38789 |
| LY6D | lymphocyte antigen 6 complex, locus D | 2.37258 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 2.35455 |
| SOSTDC1 | sclerostin domain containing 1 | 2.23662 |
| NDUFAF1 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 | 2.21312 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.20968 |
| POGLUT1 | protein O-glucosyltransferase 1 | 2.20252 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 2.19487 |
| ODAM | odontogenic, ameloblast asssociated | 2.19033 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 2.16353 |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 | 2.14835 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 2.13846 |
| PSENEN | presenilin enhancer gamma secretase subunit | 2.10685 |
| LGALS7B | lectin, galactoside-binding, soluble, 7B | 2.07266 |
| PTPN20 | protein tyrosine phosphatase, non-receptor type 20 | 2.07125 |
| GIPC2 | GIPC PDZ domain containing family, member 2 | 2.06489 |
| IVL | involucrin | 2.0437 |
| PLA2G3 | phospholipase A2, group III | 2.03898 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 2.02834 |
| SERF1A | small EDRK-rich factor 1A (telomeric) | 2.02593 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 | 2.01553 |
| HTN1 | histatin 1 | 2.01418 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GDF15 | growth differentiation factor 15 | -5.64711 |
| CDC25B | cell division cycle 25B | -5.31163 |
| PCNA | proliferating cell nuclear antigen | -5.10798 |
| TUBB6 | tubulin, beta 6 class V | -4.87503 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.84353 |
| KIF14 | kinesin family member 14 | -4.67364 |
| HSPA8 | heat shock 70kDa protein 8 | -4.48369 |
| LAP3 | leucine aminopeptidase 3 | -4.36074 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.34511 |
| MT2A | metallothionein 2A | -4.15653 |
| TRIB3 | tribbles pseudokinase 3 | -3.56257 |
| DIPK1A | divergent protein kinase domain 1A | -3.44937 |
| DDRGK1 | DDRGK domain containing 1 | -3.23713 |
| SNRPB2 | small nuclear ribonucleoprotein polypeptide B | -2.85762 |
| PUDP | pseudouridine 5'-phosphatase | -2.83628 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -2.74678 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -2.73514 |
| CDCP1 | CUB domain containing protein 1 | -2.73041 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | -2.67492 |
| HTRA1 | HtrA serine peptidase 1 | -2.63952 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -2.55616 |
| OXTR | oxytocin receptor | -2.50648 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | -2.36766 |
| PANK2 | pantothenate kinase 2 | -2.35072 |
| ZNF133 | zinc finger protein 133 | -2.34355 |
| CYBC1 | cytochrome b-245 chaperone 1 | -2.33318 |
| SMC1A | structural maintenance of chromosomes 1A | -2.28407 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -2.27903 |
| STK25 | serine/threonine kinase 25 | -2.2748 |
| GPN2 | GPN-loop GTPase 2 | -2.26467 |
| GSTT2B | glutathione S-transferase theta 2B (gene/pseudogene) | -2.26375 |
| SLC12A8 | solute carrier family 12, member 8 | -2.23777 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | -2.20367 |
| GLB1 | galactosidase, beta 1 | -2.18751 |
| CLPP | caseinolytic mitochondrial matrix peptidase proteolytic subunit | -2.12995 |
| SETD5 | SET domain containing 5 | -2.09948 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.0771 |
| GPR137B | G protein-coupled receptor 137B | -2.07212 |
| CD320 | CD320 molecule | -2.07168 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 | -2.05434 |
| TCTA | T-cell leukemia translocation altered | -2.04711 |
| CORO2B | coronin, actin binding protein, 2B | -2.03531 |
| NVL | nuclear VCP-like | -2.03111 |
