CRCGN016_MCF10A.TP53.M_24H:J06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dioxane 11.44 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:J06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 4.54835
CLNS1A chloride channel, nucleotide-sensitive, 1A 3.8436
AAMDC adipogenesis associated, Mth938 domain containing 3.48415
ALG8 ALG8, alpha-1,3-glucosyltransferase 3.4326
HBA1 hemoglobin, alpha 1 3.3906
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 3.20995
IGHMBP2 immunoglobulin mu binding protein 2 3.00165
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.96455
PKN1 protein kinase N1 2.81635
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.7988
PDK4 pyruvate dehydrogenase kinase, isozyme 4 2.58975
RSF1 remodeling and spacing factor 1 2.5225
ACAA1 acetyl-CoA acyltransferase 1 2.1783
UVRAG UV radiation resistance associated 2.1257
ARRB1 arrestin, beta 1 2.12059
WIF1 WNT inhibitory factor 1 2.09175
ATRAID all-trans retinoic acid-induced differentiation factor 2.03025
CAVIN2 caveolae associated protein 2 2.01725
PDLIM1 PDZ and LIM domain 1 2.0161

decreased expression

Symbol Name Standardized Value
VAT1 vesicle amine transport 1 -5.0433
HSPA8 heat shock 70kDa protein 8 -4.83407
FBXO21 F-box protein 21 -3.10492
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.7659
SGK1 serum/glucocorticoid regulated kinase 1 -2.53945
BAD BCL2-associated agonist of cell death -2.47078
MEIS1 Meis homeobox 1 -2.04255
AMIGO2 adhesion molecule with Ig-like domain 2 -2.02015