CRCGN016_MCF10A.TP53.M_24H:J08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isopropyl-n-(3-chloro?phenyl)carbamate 32.93 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

28 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:J08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCR4 chemokine (C-X-C motif) receptor 4 5.36313
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 4.86544
KCTD5 potassium channel tetramerization domain containing 5 4.47115
VGLL4 vestigial-like family member 4 3.03532
ACAA1 acetyl-CoA acyltransferase 1 2.87006
ALDOC aldolase C, fructose-bisphosphate 2.62198
DDR1 discoidin domain receptor tyrosine kinase 1 2.47765
COMP cartilage oligomeric matrix protein 2.42532
SIRT3 sirtuin 3 2.28067
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.12636
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 2.06299
MMP1 matrix metallopeptidase 1 2.02755

decreased expression

Symbol Name Standardized Value
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -4.44732
ATF5 activating transcription factor 5 -4.18871
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -4.00789
ANKRD10 ankyrin repeat domain 10 -3.97952
GRWD1 glutamate-rich WD repeat containing 1 -3.35996
HMG20B high mobility group 20B -3.15875
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.97997
THAP11 THAP domain containing 11 -2.90712
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.77724
ADI1 acireductone dioxygenase 1 -2.76333
KRT14 keratin 14, type I -2.7003
REXO2 RNA exonuclease 2 -2.58317
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.34018
BASP1 brain abundant, membrane attached signal protein 1 -2.23636
RPA3 replication protein A3, 14kDa -2.06342
GRB14 growth factor receptor-bound protein 14 -2.02772