| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | isopropyl-n-(3-chloro?phenyl)carbamate 10.98 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome) |
| Similar Terms | |
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105 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:J09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COMP | cartilage oligomeric matrix protein | 5.65661 |
| BMP4 | bone morphogenetic protein 4 | 4.75372 |
| CHEK1 | checkpoint kinase 1 | 4.15635 |
| CNPY3 | canopy FGF signaling regulator 3 | 4.07094 |
| RAP1GAP | RAP1 GTPase activating protein | 4.02726 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.99432 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | 3.73295 |
| HBA1 | hemoglobin, alpha 1 | 3.4843 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | 3.39851 |
| ABHD4 | abhydrolase domain containing 4 | 3.27484 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.20399 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 3.05149 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 | 2.76928 |
| TRIM68 | tripartite motif containing 68 | 2.7236 |
| CADM1 | cell adhesion molecule 1 | 2.67028 |
| PRKCQ | protein kinase C, theta | 2.63459 |
| KRABD4 | KRAB domain containing 4 | 2.60191 |
| BBS1 | Bardet-Biedl syndrome 1 | 2.48943 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.47265 |
| TTC31 | tetratricopeptide repeat domain 31 | 2.44347 |
| MFAP5 | microfibrillar associated protein 5 | 2.41869 |
| MCPH1 | microcephalin 1 | 2.37686 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | 2.37235 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | 2.36795 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 2.34999 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | 2.33506 |
| HBB | hemoglobin, beta | 2.28824 |
| THOC1 | THO complex 1 | 2.27055 |
| SLC35F5 | solute carrier family 35, member F5 | 2.26667 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 2.20915 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 2.20459 |
| KPTN | kaptin (actin binding protein) | 2.19734 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 2.16302 |
| PHF8 | PHD finger protein 8 | 2.16273 |
| CCNB1 | cyclin B1 | 2.1588 |
| SLC68A1 | solute carrier family 68 member 1 | 2.14616 |
| ADRB2 | adrenoceptor beta 2, surface | 2.12002 |
| PPWD1 | peptidylprolyl isomerase domain and WD repeat containing 1 | 2.10848 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 2.10704 |
| MRPS10 | mitochondrial ribosomal protein S10 | 2.09329 |
| PIGK | phosphatidylinositol glycan anchor biosynthesis, class K | 2.09328 |
| RBM23 | RNA binding motif protein 23 | 2.087 |
| RFX4 | regulatory factor X, 4 (influences HLA class II expression) | 2.07944 |
| FMOD | fibromodulin | 2.07097 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase | 2.05829 |
| ADA | adenosine deaminase | 2.05727 |
| CPOX | coproporphyrinogen oxidase | 2.04597 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 | 2.04525 |
| ANKRD55 | ankyrin repeat domain 55 | 2.03584 |
| MGAT4C | MGAT4 family, member C | 2.03166 |
| MRPL16 | mitochondrial ribosomal protein L16 | 2.03001 |
| HPS4 | Hermansky-Pudlak syndrome 4 | 2.02615 |
| IL12RB2 | interleukin 12 receptor, beta 2 | 2.02363 |
| MTF2 | metal response element binding transcription factor 2 | 2.02191 |
| CDK20 | cyclin-dependent kinase 20 | 2.01523 |
| BCR | breakpoint cluster region | 2.01467 |
| CEP72 | centrosomal protein 72kDa | 2.00383 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BASP1 | brain abundant, membrane attached signal protein 1 | -5.77684 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -5.02288 |
| MSMO1 | methylsterol monooxygenase 1 | -4.92745 |
| TUBA4A | tubulin, alpha 4a | -4.70429 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -4.52136 |
| KRT14 | keratin 14, type I | -4.32069 |
| TBCB | tubulin folding cofactor B | -4.13047 |
| VDAC1 | voltage-dependent anion channel 1 | -4.02832 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -3.97374 |
| SLC25A46 | solute carrier family 25, member 46 | -3.95084 |
| KIF14 | kinesin family member 14 | -3.89891 |
| YME1L1 | YME1-like 1 ATPase | -3.85905 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.83639 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -3.6945 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -3.63209 |
| TEX10 | testis expressed 10 | -3.19777 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.94424 |
| THAP11 | THAP domain containing 11 | -2.91941 |
| TSPAN3 | tetraspanin 3 | -2.82308 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -2.65106 |
| BOLA2B | bolA family member 2B | -2.64561 |
| TMEM147 | transmembrane protein 147 | -2.57367 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | -2.56692 |
| SDHAF1 | succinate dehydrogenase complex assembly factor 1 | -2.54572 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -2.54396 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -2.45651 |
| CSNK1G3 | casein kinase 1, gamma 3 | -2.40773 |
| STXBP2 | syntaxin binding protein 2 | -2.39081 |
| SOAT2 | sterol O-acyltransferase 2 | -2.36063 |
| SLC16A6 | solute carrier family 16, member 6 | -2.31006 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -2.29645 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | -2.24377 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.21479 |
| CIAO2B | cytosolic iron-sulfur assembly component 2B | -2.2138 |
| CAPN2 | calpain 2, (m/II) large subunit | -2.20947 |
| TBC1D10B | TBC1 domain family, member 10B | -2.20496 |
| USF2 | upstream transcription factor 2, c-fos interacting | -2.19811 |
| PIH1D1 | PIH1 domain containing 1 | -2.19503 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -2.1783 |
| LOC112694756 | uncharaterized LOC112694756 | -2.11702 |
| BCL7B | B-cell CLL/lymphoma 7B | -2.11063 |
| TP53BP2 | tumor protein p53 binding protein 2 | -2.06719 |
| RFXANK | regulatory factor X-associated ankyrin-containing protein | -2.05916 |
| FIBP | fibroblast growth factor (acidic) intracellular binding protein | -2.05873 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -2.0502 |
| ICAM3 | intercellular adhesion molecule 3 | -2.03323 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.00197 |
| TNNT3 | troponin T type 3 (skeletal, fast) | -2.00023 |
