CRCGN016_MCF10A.TP53.M_24H:J10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimethylnitrosamine 99.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:J10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AXIN1 axin 1 4.20653
PPARG peroxisome proliferator-activated receptor gamma 3.41467
FKBP14 FK506 binding protein 14, 22 kDa 2.91015
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.58488
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.25905
ACAA1 acetyl-CoA acyltransferase 1 2.19303
CGRRF1 cell growth regulator with ring finger domain 1 2.10086
CREG1 cellular repressor of E1A-stimulated genes 1 2.05016
NFIL3 nuclear factor, interleukin 3 regulated 2.02469
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.00748

decreased expression

Symbol Name Standardized Value
CAB39 calcium binding protein 39 -3.8576
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.82567
THAP11 THAP domain containing 11 -3.66496
TEX10 testis expressed 10 -3.42183
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.39704
TNIP1 TNFAIP3 interacting protein 1 -2.96014
ATG3 autophagy related 3 -2.86709
COTL1 coactosin-like F-actin binding protein 1 -2.76067
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.40332
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -2.37324
ATOX1 antioxidant 1 copper chaperone -2.36179
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.33046
MTFR1 mitochondrial fission regulator 1 -2.05834