CRCGN016_MCF10A.TP53.M_24H:J13 Gene Set
Genes
29 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:J13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
3.90187
|
|
RPL39L
|
ribosomal protein L39-like
|
3.60507
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.19846
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
3.19472
|
|
LAGE3
|
L antigen family, member 3
|
2.98806
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
2.7163
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.61589
|
|
STAT3
|
signal transducer and activator of transcription 3 (acute-phase response factor)
|
2.49621
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.46783
|
|
SDHB
|
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
|
2.44485
|
|
CHEK1
|
checkpoint kinase 1
|
2.34982
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.19875
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.1921
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.16558
|
|
SUMO4
|
small ubiquitin-like modifier 4
|
2.01895
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-7.43357
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-4.257
|
|
HAT1
|
histone acetyltransferase 1
|
-3.899
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.491
|
|
PMM2
|
phosphomannomutase 2
|
-3.02541
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-2.74114
|
|
S100A8
|
S100 calcium binding protein A8
|
-2.44001
|
|
KRT14
|
keratin 14, type I
|
-2.44001
|
|
MSMO1
|
methylsterol monooxygenase 1
|
-2.44001
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-2.40111
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.36603
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.19094
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.08455
|
|
SQLE
|
squalene epoxidase
|
-2.05814
|
