CRCGN016_MCF10A.TP53.M_24H:J18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:J18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COMP cartilage oligomeric matrix protein 3.35122
PRKCH protein kinase C, eta 3.10498
KIF5C kinesin family member 5C 2.78719
CNRIP1 cannabinoid receptor interacting protein 1 2.65471
SMAD3 SMAD family member 3 2.12007
LOC122526780 uncharacterized LOC122526780 2.06432
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2.03576

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -8.23532
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.85932
SLC35F2 solute carrier family 35, member F2 -4.51893
SGK1 serum/glucocorticoid regulated kinase 1 -3.86891
MFSD12 major facilitator superfamily domain containing 12 -3.27672
NGRN neugrin, neurite outgrowth associated -2.64124
TUBA4A tubulin, alpha 4a -2.46651
LOC100533997 MAGEA10-MAGEA5 readthrough -2.2456
MAGEA1 melanoma antigen family A1 -2.18509
RHOT2 ras homolog family member T2 -2.01308