CRCGN016_MCF10A.TP53.M_24H:J19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrobenzene 102.79 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:J19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD4 abhydrolase domain containing 4 4.58072
MAMLD1 mastermind-like domain containing 1 3.85957
RAB11FIP2 RAB11 family interacting protein 2 (class I) 3.47146
SNX11 sorting nexin 11 3.33503
TBX2 T-box 2 2.59739
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.5858
IGHMBP2 immunoglobulin mu binding protein 2 2.57842
SLIT2 slit homolog 2 (Drosophila) 2.20274
STX17 syntaxin 17 2.17075
F8A2 coagulation factor VIII-associated 2 2.15442
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.12967
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 2.11024
EVL Enah/Vasp-like 2.03897
BCAS3 breast carcinoma amplified sequence 3 2.03496

decreased expression

Symbol Name Standardized Value
DNM1L dynamin 1-like -4.3723
UBE3C ubiquitin protein ligase E3C -4.29278
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.89143
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.87378
CLTB clathrin, light chain B -3.20101
RBM34 RNA binding motif protein 34 -3.10452
JMJD6 jumonji domain containing 6 -3.09454
TUBA4A tubulin, alpha 4a -2.74678
REEP5 receptor accessory protein 5 -2.55885
CD58 CD58 molecule -2.47964
LINC02762 long intergenic non-protein coding RNA 2762 -2.34959
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -2.28325
NDEL1 nudE neurodevelopment protein 1-like 1 -2.2751
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.26433
KRT14 keratin 14, type I -2.22065
MXRA7 matrix-remodelling associated 7 -2.15094
PTPRE protein tyrosine phosphatase, receptor type, E -2.0595
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.05193