CRCGN016_MCF10A.TP53.M_24H:J20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrobenzene 34.26 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:J20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RPL39L ribosomal protein L39-like 3.65251
ARID5B AT rich interactive domain 5B (MRF1-like) 3.31676
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.29634
SNAP25 synaptosomal-associated protein, 25kDa 2.85057
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.64477
MMP1 matrix metallopeptidase 1 2.50866
BACE2 beta-site APP-cleaving enzyme 2 2.12709
COQ8A coenzyme Q8A 2.08683

decreased expression

Symbol Name Standardized Value
CCDC86 coiled-coil domain containing 86 -3.89534
SGK1 serum/glucocorticoid regulated kinase 1 -3.32734
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.25927
HMG20B high mobility group 20B -3.13191
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.02975
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.49389
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) -2.44826
QPCT glutaminyl-peptide cyclotransferase -2.14768
MAGEC1 melanoma antigen family C1 -2.01243