CRCGN016_MCF10A.TP53.M_24H:J21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrobenzene 11.42 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:J21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CNRIP1 cannabinoid receptor interacting protein 1 5.305
TSEN2 TSEN2 tRNA splicing endonuclease subunit 4.7131
MAP7 microtubule-associated protein 7 4.52738
KLHL9 kelch-like family member 9 3.87966
ACAA1 acetyl-CoA acyltransferase 1 2.84993
FZD7 frizzled class receptor 7 2.53826
BZW2 basic leucine zipper and W2 domains 2 2.47931
LLGL2 lethal giant larvae homolog 2 (Drosophila) 2.15879
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 2.08871
ERMP1 endoplasmic reticulum metallopeptidase 1 2.07677
CNPY3 canopy FGF signaling regulator 3 2.05033
MGST3 microsomal glutathione S-transferase 3 2.04876
USP6NL USP6 N-terminal like 2.02987

decreased expression

Symbol Name Standardized Value
BAG3 BCL2-associated athanogene 3 -5.32533
KIF14 kinesin family member 14 -4.77854
MT1X metallothionein 1X -4.13118
SGK1 serum/glucocorticoid regulated kinase 1 -3.79738
IFRD2 interferon-related developmental regulator 2 -3.39471
NGRN neugrin, neurite outgrowth associated -3.37551
TMEM115 transmembrane protein 115 -2.78994
MT2A metallothionein 2A -2.57364
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.5335
GDF15 growth differentiation factor 15 -2.42158
MTERF3 mitochondrial transcription termination factor 3 -2.35448
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -2.3191
MUC6 mucin 6, oligomeric mucus/gel-forming -2.30852
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -2.29542
SFMBT1 Scm-like with four mbt domains 1 -2.06507
TUSC2 tumor suppressor candidate 2 -2.03765
SYNC syncoilin, intermediate filament protein -2.01138
DUSP13A dual specificity phosphatase 13A -2.0035