CRCGN016_MCF10A.TP53.M_24H:J22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description pyrazinamide 99.96 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:J22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CNRIP1 cannabinoid receptor interacting protein 1 5.09715
SPAG4 sperm associated antigen 4 4.10025
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 4.00821
ZNF586 zinc finger protein 586 3.19374
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.06765
MAP7 microtubule-associated protein 7 2.94894
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.83297
BZW2 basic leucine zipper and W2 domains 2 2.80144
ABHD6 abhydrolase domain containing 6 2.7321
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.4542
USP6NL USP6 N-terminal like 2.37022
WFS1 Wolfram syndrome 1 (wolframin) 2.18743
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.11601
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.03029
BAX BCL2-associated X protein 2.01585

decreased expression

Symbol Name Standardized Value
BAG3 BCL2-associated athanogene 3 -3.53784
TM9SF3 transmembrane 9 superfamily member 3 -3.48913
TXNDC9 thioredoxin domain containing 9 -3.04685
TCTA T-cell leukemia translocation altered -2.91792
GDF15 growth differentiation factor 15 -2.89157
CCNB2 cyclin B2 -2.8791
ACOT9 acyl-CoA thioesterase 9 -2.83924
NPDC1 neural proliferation, differentiation and control, 1 -2.82684
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.68433
PCNA proliferating cell nuclear antigen -2.67554
SMC1A structural maintenance of chromosomes 1A -2.07527
TUBA4A tubulin, alpha 4a -2.05791
PCCB propionyl CoA carboxylase, beta polypeptide -2.04552
VRTN vertebrae development associated -2.00918