CRCGN016_MCF10A.TP53.M_24H:K01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phthalamide 100.3 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:K01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.767
CGRRF1 cell growth regulator with ring finger domain 1 3.72524
CLNS1A chloride channel, nucleotide-sensitive, 1A 3.10052
ALG8 ALG8, alpha-1,3-glucosyltransferase 3.0013
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.79164
THAP12 THAP domain containing 12 2.53811
PDGFA platelet-derived growth factor alpha polypeptide 2.25499
AAMDC adipogenesis associated, Mth938 domain containing 2.21881
PKN1 protein kinase N1 2.1449
ADIPOR2 adiponectin receptor 2 2.10584
RIC8A RIC8 guanine nucleotide exchange factor A 2.07803
RSF1 remodeling and spacing factor 1 2.02

decreased expression

Symbol Name Standardized Value
SCYL3 SCY1-like 3 (S. cerevisiae) -5.53369
TES testin LIM domain protein -3.55746
MT1X metallothionein 1X -2.62917
SNCAIP synuclein, alpha interacting protein -2.43407
REEP5 receptor accessory protein 5 -2.36791
SQOR sulfide quinone oxidoreductase -2.25204
STXBP2 syntaxin binding protein 2 -2.22708
ATP11B ATPase, class VI, type 11B -2.11618
PRL prolactin -2.05329