CRCGN016_MCF10A.TP53.M_24H:K02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phthalamide 33.43 um perturbation at 24 h in MCF10A.TP53.M (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN016_MCF10A.TP53.M_24H:K02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
BACE2 beta-site APP-cleaving enzyme 2 2.99507
CXCR4 chemokine (C-X-C motif) receptor 4 2.89733
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.63575
ACAA1 acetyl-CoA acyltransferase 1 2.52404
TLCD3A TLC domain containing 3A 2.41045
GLOD4 glyoxalase domain containing 4 2.35044
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.31267
CHEK1 checkpoint kinase 1 2.11514
SQOR sulfide quinone oxidoreductase 2.02209

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -4.9742
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -3.68804
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.96609